A gel that regrows tooth enamel? UK team aims for first product in 2027
The University of Nottingham has developed a fluoride-free, protein-based gel that fills microscopic cracks in enamel and draws calcium and phosphate from saliva to grow a new mineral layer aligned with the existing tooth. In lab tests simulating brushing, chewing and acidic food, the restored enamel performed like healthy enamel. A spin-out company is commercialising it, aiming for a first product in 2027.
What it means for you
Lost enamel has never been able to grow back; this could help sensitivity and erosion in future, but so far the results are from the lab only.
Editors' take: the background
Enamel is the hardest tissue in the body but has no living cells, so once it is worn or dissolved by acid the body cannot grow it back. Fluoride toothpaste helps early weak spots remineralise, but it cannot replace enamel that has gone.
Moving from the lab to the clinic usually takes human trials and regulatory approval, which can take years. For now, be sceptical of products claiming to regrow enamel instantly.
Key points
- Lab results only; no human trial data yet
- First product targeted for 2027
- For now: fewer acidic drinks and fluoride toothpaste
Source: University of Nottingham (via ScienceDaily)
This is a news summary written by our editors, not medical advice. Please refer to the original source and seek professional advice for your own situation.
Questions readers ask
Does sensitivity mean my enamel is gone?
Not necessarily. Common causes include enamel wear, receding gums exposing the root, decay or a cracked tooth. Get it checked to find the cause.
How can I protect my enamel now?
Cut down on acidic drinks, use fluoride toothpaste and don't brush too hard. If you grind your teeth at night, ask your dentist about a night guard.
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